PinnyPeptide

CJC-1295 vs Ipamorelin

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

CJC-1295

Growth Hormone

Long-acting growth hormone releasing hormone analog for sustained GH and IGF-1 elevation.

Peptide B

Ipamorelin

Growth Hormone

Selective growth hormone secretagogue with minimal side effects.

Typical vial

2 mg

Typical dose

100-300 mcg

Half-life

~30 minutes (no DAC) / 6-8 days (with DAC)

FDA status

Not FDA approved for human use.

Typical vial

5 mg

Typical dose

100-300 mcg

Half-life

~2 hours

FDA status

Not FDA approved for human use. Clinical development discont…

CJC-1295 effects

  • Increases growth hormone secretion from the pituitary
  • Elevates IGF-1 levels for sustained anabolic signaling
  • Promotes fat metabolism and improved body composition
  • Supports deeper, more restorative sleep patterns
  • Enhances recovery from exercise and tissue repair

Ipamorelin effects

  • Selectively stimulates growth hormone release
  • Promotes fat metabolism without affecting cortisol
  • Supports lean muscle growth and recovery
  • Improves sleep quality through enhanced GH pulsatility
  • Does not significantly increase appetite or prolactin

CJC-1295 side effects

  • Injection site redness, swelling, or irritation
  • Water retention and bloating
  • Tingling or numbness in the extremities
  • Headache
  • Dizziness or flushing shortly after injection

Ipamorelin side effects

  • Mild head rush or flushing immediately after injection
  • Transient water retention
  • Injection site irritation
  • Occasional lightheadedness

CJC-1295 dosing ranges

Anti-aging and recovery (Mod GRF)

100 mcg · Once to three times daily (SubQ) · 8-12 weeks

Body composition (Mod GRF + Ipamorelin)

100-300 mcg · Two to three times daily · 8-12 weeks

CJC-1295 with DAC

1000-2000 mcg · Once or twice weekly · 8-12 weeks

Ipamorelin dosing ranges

GH optimization and anti-aging

100-300 mcg · Two to three times daily (SubQ) · 8-12 weeks

Combined with CJC-1295 (Mod GRF)

100-200 mcg · Two to three times daily · 8-12 weeks

CJC-1295 vs Ipamorelin — common questions

What is the difference between CJC-1295 and Ipamorelin?

CJC-1295: Long-acting growth hormone releasing hormone analog for sustained GH and IGF-1 elevation. Typical dose 100-300 mcg. Ipamorelin: Selective growth hormone secretagogue with minimal side effects. Typical dose 100-300 mcg. Both fall under the Growth Hormone category.

Can you stack CJC-1295 and Ipamorelin?

Stacking CJC-1295 with Ipamorelin is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, CJC-1295 or Ipamorelin?

CJC-1295 is typically dosed: Once to three times daily (SubQ) for Anti-aging and recovery (Mod GRF); Two to three times daily for Body composition (Mod GRF + Ipamorelin); Once or twice weekly for CJC-1295 with DAC. Ipamorelin is typically dosed: Two to three times daily (SubQ) for GH optimization and anti-aging; Two to three times daily for Combined with CJC-1295 (Mod GRF).

Are CJC-1295 and Ipamorelin FDA approved?

CJC-1295: Not FDA approved for human use. Ipamorelin: Not FDA approved for human use. Clinical development discontinued by Novo Nordisk.

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