PinnyPeptide

AOD-9604 vs FTPP-Adipotide

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

AOD-9604

Weight Management

Fat-metabolizing fragment of human growth hormone without growth-promoting effects.

Peptide B

FTPP-Adipotide

Weight Management

Vasculature-targeting peptide that selectively destroys adipose blood vessels.

Typical vial

5 mg

Typical dose

250-500 mcg

Half-life

~30-60 minutes

FDA status

Not FDA approved as a drug. Granted GRAS status as a food ad…

Typical vial

5 mg

Typical dose

Per kg dosing (research-only) mcg

Half-life

~hours

FDA status

Not FDA approved.

AOD-9604 effects

  • Stimulates lipolysis (fat breakdown) in adipose tissue
  • Inhibits lipogenesis (new fat formation)
  • Does not affect blood glucose or insulin levels
  • Does not elevate IGF-1 or bind the GH receptor
  • May support cartilage repair (emerging research)

FTPP-Adipotide effects

  • Selective destruction of white adipose tissue vasculature
  • Rapid weight and fat loss in primate models
  • Improved insulin sensitivity
  • Brown adipose tissue largely spared
  • Mechanism distinct from lipolytic / appetite-suppressing peptides

AOD-9604 side effects

  • Injection site irritation or redness
  • Occasional headache
  • Mild nausea (uncommon)
  • Transient lightheadedness

FTPP-Adipotide side effects

  • Renal toxicity (prohibitin expressed in kidney vasculature) — significant safety concern
  • Possible damage to other prohibitin-expressing vascular beds
  • Injection-site reactions
  • Limited human safety data
  • Acute inflammatory response from adipose vascular death

AOD-9604 dosing ranges

Fat loss and body composition

250-500 mcg · Once daily (SubQ) · 8-12 weeks

FTPP-Adipotide dosing ranges

Animal research (rhesus monkey model)

0.43 mg/kg · Daily SubQ × 28 days · Per published protocol

Human self-experimentation

Not recommended · — · —

Full AOD-9604 guide → Full FTPP-Adipotide guide →

AOD-9604 vs FTPP-Adipotide — common questions

What is the difference between AOD-9604 and FTPP-Adipotide?

AOD-9604: Fat-metabolizing fragment of human growth hormone without growth-promoting effects. Typical dose 250-500 mcg. FTPP-Adipotide: Vasculature-targeting peptide that selectively destroys adipose blood vessels. Typical dose Per kg dosing (research-only) mcg. Both fall under the Weight Management category.

Can you stack AOD-9604 and FTPP-Adipotide?

Stacking AOD-9604 with FTPP-Adipotide is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, AOD-9604 or FTPP-Adipotide?

AOD-9604 is typically dosed: Once daily (SubQ) for Fat loss and body composition. FTPP-Adipotide is typically dosed: Daily SubQ × 28 days for Animal research (rhesus monkey model); — for Human self-experimentation.

Are AOD-9604 and FTPP-Adipotide FDA approved?

AOD-9604: Not FDA approved as a drug. Granted GRAS status as a food additive in 2014. FTPP-Adipotide: Not FDA approved.

Related peptide comparisons

aod-9604 vs cjc-1295aod-9604 vs hgh-fragment-176-191aod-9604 vs ipamorelinaod-9604 vs retatrutideaod-9604 vs semaglutideftpp-adipotide vs hgh-fragment-176-191

Tracking either of these?

Log doses, automate injection site rotation, and never lose track of where you last pinned. Free forever.

Get Started Free