PinnyPeptide

AOD-9604 vs HGH Fragment 176-191

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

AOD-9604

Weight Management

Fat-metabolizing fragment of human growth hormone without growth-promoting effects.

Peptide B

HGH Fragment 176-191

Weight Management

The unmodified C-terminal fragment of growth hormone — the original lipolytic peptide.

Typical vial

5 mg

Typical dose

250-500 mcg

Half-life

~30-60 minutes

FDA status

Not FDA approved as a drug. Granted GRAS status as a food ad…

Typical vial

5 mg

Typical dose

250-500 mcg

Half-life

~30 minutes

FDA status

Not FDA approved. Distinct from AOD-9604, which holds GRAS s…

AOD-9604 effects

  • Stimulates lipolysis (fat breakdown) in adipose tissue
  • Inhibits lipogenesis (new fat formation)
  • Does not affect blood glucose or insulin levels
  • Does not elevate IGF-1 or bind the GH receptor
  • May support cartilage repair (emerging research)

HGH Fragment 176-191 effects

  • Stimulates lipolysis (fat breakdown) in adipose tissue
  • Inhibits lipogenesis (new fat formation)
  • Does not bind the GH receptor
  • Does not raise IGF-1 or affect blood glucose
  • Targets stubborn / subcutaneous fat in cut-phase protocols

AOD-9604 side effects

  • Injection site irritation or redness
  • Occasional headache
  • Mild nausea (uncommon)
  • Transient lightheadedness

HGH Fragment 176-191 side effects

  • Injection-site irritation or redness
  • Occasional headache
  • Mild fatigue at the start of a cycle (rare)
  • Transient flushing

AOD-9604 dosing ranges

Fat loss and body composition

250-500 mcg · Once daily (SubQ) · 8-12 weeks

HGH Fragment 176-191 dosing ranges

Fat loss / body recomposition

250-500 mcg · Once daily, morning, on an empty stomach (SubQ) · 8-12 weeks

Split-dose protocol for stubborn fat

250 mcg · Twice daily (morning + pre-cardio), fasted · 8-12 weeks

AOD-9604 vs HGH Fragment 176-191 — common questions

What is the difference between AOD-9604 and HGH Fragment 176-191?

AOD-9604: Fat-metabolizing fragment of human growth hormone without growth-promoting effects. Typical dose 250-500 mcg. HGH Fragment 176-191: The unmodified C-terminal fragment of growth hormone — the original lipolytic peptide. Typical dose 250-500 mcg. Both fall under the Weight Management category.

Can you stack AOD-9604 and HGH Fragment 176-191?

Stacking AOD-9604 with HGH Fragment 176-191 is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, AOD-9604 or HGH Fragment 176-191?

AOD-9604 is typically dosed: Once daily (SubQ) for Fat loss and body composition. HGH Fragment 176-191 is typically dosed: Once daily, morning, on an empty stomach (SubQ) for Fat loss / body recomposition; Twice daily (morning + pre-cardio), fasted for Split-dose protocol for stubborn fat.

Are AOD-9604 and HGH Fragment 176-191 FDA approved?

AOD-9604: Not FDA approved as a drug. Granted GRAS status as a food additive in 2014. HGH Fragment 176-191: Not FDA approved. Distinct from AOD-9604, which holds GRAS status as a food additive.

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