PinnyPeptide

AOD-9604 vs Ipamorelin

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

AOD-9604

Weight Management

Fat-metabolizing fragment of human growth hormone without growth-promoting effects.

Peptide B

Ipamorelin

Growth Hormone

Selective growth hormone secretagogue with minimal side effects.

Typical vial

5 mg

Typical dose

250-500 mcg

Half-life

~30-60 minutes

FDA status

Not FDA approved as a drug. Granted GRAS status as a food ad…

Typical vial

5 mg

Typical dose

100-300 mcg

Half-life

~2 hours

FDA status

Not FDA approved for human use. Clinical development discont…

AOD-9604 effects

  • Stimulates lipolysis (fat breakdown) in adipose tissue
  • Inhibits lipogenesis (new fat formation)
  • Does not affect blood glucose or insulin levels
  • Does not elevate IGF-1 or bind the GH receptor
  • May support cartilage repair (emerging research)

Ipamorelin effects

  • Selectively stimulates growth hormone release
  • Promotes fat metabolism without affecting cortisol
  • Supports lean muscle growth and recovery
  • Improves sleep quality through enhanced GH pulsatility
  • Does not significantly increase appetite or prolactin

AOD-9604 side effects

  • Injection site irritation or redness
  • Occasional headache
  • Mild nausea (uncommon)
  • Transient lightheadedness

Ipamorelin side effects

  • Mild head rush or flushing immediately after injection
  • Transient water retention
  • Injection site irritation
  • Occasional lightheadedness

AOD-9604 dosing ranges

Fat loss and body composition

250-500 mcg · Once daily (SubQ) · 8-12 weeks

Ipamorelin dosing ranges

GH optimization and anti-aging

100-300 mcg · Two to three times daily (SubQ) · 8-12 weeks

Combined with CJC-1295 (Mod GRF)

100-200 mcg · Two to three times daily · 8-12 weeks

Full AOD-9604 guide → Full Ipamorelin guide →

AOD-9604 vs Ipamorelin — common questions

What is the difference between AOD-9604 and Ipamorelin?

AOD-9604: Fat-metabolizing fragment of human growth hormone without growth-promoting effects. Typical dose 250-500 mcg. Ipamorelin: Selective growth hormone secretagogue with minimal side effects. Typical dose 100-300 mcg. Both fall under the Weight Management and Growth Hormone categories.

Can you stack AOD-9604 and Ipamorelin?

Stacking AOD-9604 with Ipamorelin is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, AOD-9604 or Ipamorelin?

AOD-9604 is typically dosed: Once daily (SubQ) for Fat loss and body composition. Ipamorelin is typically dosed: Two to three times daily (SubQ) for GH optimization and anti-aging; Two to three times daily for Combined with CJC-1295 (Mod GRF).

Are AOD-9604 and Ipamorelin FDA approved?

AOD-9604: Not FDA approved as a drug. Granted GRAS status as a food additive in 2014. Ipamorelin: Not FDA approved for human use. Clinical development discontinued by Novo Nordisk.

Related peptide comparisons

aod-9604 vs cjc-1295aod-9604 vs ftpp-adipotideaod-9604 vs hgh-fragment-176-191aod-9604 vs retatrutideaod-9604 vs semaglutidecjc-1295 vs ipamorelin

Tracking either of these?

Log doses, automate injection site rotation, and never lose track of where you last pinned. Free forever.

Get Started Free