Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.
Peptide A
Growth Hormone
Selective growth hormone secretagogue with minimal side effects.
Peptide B
Growth Hormone
A locally-acting IGF-1 splice variant released by muscle in response to mechanical load.
Typical vial
5 mg
Typical dose
100-300 mcg
Half-life
~2 hours
FDA status
Not FDA approved for human use. Clinical development discont…
Typical vial
2 mg
Typical dose
200-400 mcg
Half-life
~5-7 minutes (MGF); ~2-3 days (PEG-MGF)
FDA status
Not FDA approved for any indication.
Ipamorelin effects
MGF (Mechano Growth Factor) effects
Ipamorelin side effects
MGF (Mechano Growth Factor) side effects
Ipamorelin dosing ranges
GH optimization and anti-aging
100-300 mcg · Two to three times daily (SubQ) · 8-12 weeks
Combined with CJC-1295 (Mod GRF)
100-200 mcg · Two to three times daily · 8-12 weeks
MGF (Mechano Growth Factor) dosing ranges
Localized muscle repair (non-pegylated)
200-300 mcg per site · Post-workout, into the worked muscle (intramuscular) · 3-4 weeks per cycle
Systemic muscle recovery (PEG-MGF)
200-400 mcg · Twice weekly (SubQ) · 4-6 weeks per cycle
Ipamorelin: Selective growth hormone secretagogue with minimal side effects. Typical dose 100-300 mcg. MGF (Mechano Growth Factor): A locally-acting IGF-1 splice variant released by muscle in response to mechanical load. Typical dose 200-400 mcg. Both fall under the Growth Hormone category.
Stacking Ipamorelin with MGF (Mechano Growth Factor) is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.
Ipamorelin is typically dosed: Two to three times daily (SubQ) for GH optimization and anti-aging; Two to three times daily for Combined with CJC-1295 (Mod GRF). MGF (Mechano Growth Factor) is typically dosed: Post-workout, into the worked muscle (intramuscular) for Localized muscle repair (non-pegylated); Twice weekly (SubQ) for Systemic muscle recovery (PEG-MGF).
Ipamorelin: Not FDA approved for human use. Clinical development discontinued by Novo Nordisk. MGF (Mechano Growth Factor): Not FDA approved for any indication.
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